“Laboratory quality even without a cold chain” – from wallstreet-online.de

Laboratory quality even without a cold chain: Are inexpensive PCR tests the solution?

However, in order to be able to use the more reliable PCR tests across the board, the cost factor should also play a role. The usual PCR laboratory tests usually require a complex cold chain to ensure the test quality. The electricity, space and time requirements are reflected in the price. But recent innovations in the test equipment market could change that. Bechtold and Gregorini promise to enable PCR tests for less than 10 euros each. The two graduates from ETH Zurich have succeeded in developing a test device that ensures laboratory quality even without cooling and can be used on the go. This should make meaningful test results available to the general public. In fact, the cost advantage could allow for plans for a government-funded PCR testing strategy, such as that outlined in a Bundestag  application were formulated, become somewhat more likely again. At least when the emergency of a corona autumn wave comes, as  Federal Health Minister Karl Lauterbach (SPD) already  fears.

 

 

Modern corona tests: A blueprint for infection protection worldwide 

According  to the United Nations Biodiversity Council (IPBES)  , pandemics could occur more frequently in the future than before. IPBES expert Peter Daszak even sees them as an “existential threat to humanity” if biodiversity is not protected. This means that tests that can be used worldwide and with little effort could become increasingly important as an instrument for protection against infection. Some of the corona test devices like those from the Diaxxo AG  are therefore already designed in such a way that other viruses can also be diagnosed with them. In this way, other contagious diseases such as malaria or dengue fever could be diagnosed quickly and health systems prevented from collapsing. Even if it is not yet certain how the corona situation and future pandemics will develop: In the eyes of many experts, an effective test strategy remains an important basis for interrupting chains of infection and taking targeted protective measures.

Full article (in German):   

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Covid Variants

diaxxoPod (RUO)

Description

Our in-vitro diagnostic test cartridge based on rapid Polymerase Chain Reaction (PCR) amplification technology. This cartridge can reliably detect and distinguish the mutants from UK (20I/501Y.V1, B.1.1.7 – VOC-202012/01) as well as the South African mutation (B.1.351 lineage).

The test cartridge is aimed to improve the public health situation by rapidly enabling the detection of variants of concern. The cartridge is designed for qualitative detection of variants of interest of the SARS-CoV-2 Viral RNA in saliva samples and it works in conjuction with diaxxoPCR.

Specs

  • Fully preloaded and only require addition of purified sample
  • Results in approx. 30 minutes

Workflow

The test cartridges are sold with all the necessary reagents pre-loaded in the reaction wells. The use of the test cartridges is therefore extremely simple:

  • Apply the sample (viral RNA)
  • Apply water in the control wells and the cover fluid
  • Insert the cartrdige in diaxxoPCR, press a button, drink a coffee and check your results.

Notes & Instructions

  • The cartridges are supplied in a vacuum-sealed bag in order to ensure a long shelf life at room temperature.
  • Detailed instructions about how to use the cartridges and the devices are provided

SARS-CoV-2

diaxxoPod

Description

This SARS-CoV-2 cartridge is based on the US Centers for Disease Control and Prevention (CDC) RT-PCR test for 2019-nCoV. The assay detects 2 parts of the N gene specific for Sars-CoV-2. In addition, an extraction control for Human RNAse P is also included. The cartridge is designed to work in combination with saliva samples and in conjuction with our diaxxoPCR.

Specs

  • Functionally validated and confirmed template-free to cycle 45 by NTC testing
  •  Fully preloaded and only require addition of purified DNA/RNA
  • Results within 30 minutes

Workflow

The test cartridges are sold with all the necessary reagents pre-loaded in the reaction wells. The use of the test cartridges is therefore extremely simple:

  • Apply the sample (viral RNA)
  • Apply water in the control wells and the cover fluid
  • Insert the cartrdige in diaxxoPCR, press a button, drink a coffee and check your results.

Notes & Instructions

  • The cartridges are supplied in a vacuum-sealed bag in order to ensure a long shelf life at room temperature.
  • Detailed instructions about how to use the cartridges and the devices are provided

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