Michele Gregorini presented Diaxxo to Italian President Mattarella and Swiss president Cassis

On Wednesday, 30 November, President Mattarella and President Cassis have visited ETH Zurich, where they listened to the presentation of four researchers, including Dr. Michele Gregorini.

  by Lara Pfuderer on ethz.ch

Michele completed his doctorate at ETH Zurich and he is now a Pioneer Fellow. Together with Dr. Bechtold and Prof. Stark, they co-founded the ETH spin-off Diaxxo, which develops DNA analysis systems that enable a precise, reliable, rapid and cost-effective diagnosis. Their point-of-care PCR tests deliver results within 30 minutes and allow doctors to detect and treat diseases accordingly quickly. Since the tests do not require a complex infrastructure and only cost around five francs, they are particularly suitable for resource-limited settings.

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Covid Variants

diaxxoPod (RUO)

Description

Our in-vitro diagnostic test cartridge based on rapid Polymerase Chain Reaction (PCR) amplification technology. This cartridge can reliably detect and distinguish the mutants from UK (20I/501Y.V1, B.1.1.7 – VOC-202012/01) as well as the South African mutation (B.1.351 lineage).

The test cartridge is aimed to improve the public health situation by rapidly enabling the detection of variants of concern. The cartridge is designed for qualitative detection of variants of interest of the SARS-CoV-2 Viral RNA in saliva samples and it works in conjuction with diaxxoPCR.

Specs

  • Fully preloaded and only require addition of purified sample
  • Results in approx. 30 minutes

Workflow

The test cartridges are sold with all the necessary reagents pre-loaded in the reaction wells. The use of the test cartridges is therefore extremely simple:

  • Apply the sample (viral RNA)
  • Apply water in the control wells and the cover fluid
  • Insert the cartrdige in diaxxoPCR, press a button, drink a coffee and check your results.

Notes & Instructions

  • The cartridges are supplied in a vacuum-sealed bag in order to ensure a long shelf life at room temperature.
  • Detailed instructions about how to use the cartridges and the devices are provided

SARS-CoV-2

diaxxoPod

Description

This SARS-CoV-2 cartridge is based on the US Centers for Disease Control and Prevention (CDC) RT-PCR test for 2019-nCoV. The assay detects 2 parts of the N gene specific for Sars-CoV-2. In addition, an extraction control for Human RNAse P is also included. The cartridge is designed to work in combination with saliva samples and in conjuction with our diaxxoPCR.

Specs

  • Functionally validated and confirmed template-free to cycle 45 by NTC testing
  •  Fully preloaded and only require addition of purified DNA/RNA
  • Results within 30 minutes

Workflow

The test cartridges are sold with all the necessary reagents pre-loaded in the reaction wells. The use of the test cartridges is therefore extremely simple:

  • Apply the sample (viral RNA)
  • Apply water in the control wells and the cover fluid
  • Insert the cartrdige in diaxxoPCR, press a button, drink a coffee and check your results.

Notes & Instructions

  • The cartridges are supplied in a vacuum-sealed bag in order to ensure a long shelf life at room temperature.
  • Detailed instructions about how to use the cartridges and the devices are provided

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